Recent studies of early development in a number of ivertebrate and vertebrate species have suggested that growth factors and their receptors may play important roles in differentiation as well as cell proliferation. In the mouse embryo, the expression of the receptors for insulin and insulin‐like growth factors I and II (IGF‐I and ‐II) are temporally regulated. The ontogeny of receptor and ligand expression within the insulin and IGF gene family suggests that the very earliest stages of mammalian embryogenesis may be (...) subject to regulation by autocrine and paracrine factors from maternal and embryonic sources. (shrink)

Since its founding in 1943, Medievalia et Humanistica has won worldwide recognition as the first scholarly publication in America to devote itself entirely to medieval and Renaissance studies. Since 1970, a new series, sponsored by the Modern Language Association of America and edited by an international board of distinguished scholars and critics, has published interdisciplinary articles. In yearly hardbound volumes, the new series publishes significant scholarship, criticism, and reviews treating all facets of medieval and Renaissance culture: history, art, literature, music, (...) science, law, economics, and philosophy. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:160 BOOK REVIEWS ary. The latter dispose toward {mediate) and help in the expression of (pertain to the use of) the grace of the Spirit. In professing the priority of the Spirit, The Reshaping of Catholicism could hardly be in greater agreement with the Summa theologiae. This theme in Dulles suggests how Aquinas can be linked to ecclesial renewal: Aquinas's thought on the New Law can assist the Church (...) in continually re-acquiring its own divinely given internal order. FR. THOMAS HUGHSON, S.J. Pontificial Biblical Institute,!erusalem; Marquette University, Milwaukee, Wisconsin Choice: The Essential Element in Human Action. By ALAN DoNAGAN. Studies in Philosophical Psychology, R. F. Holland, ed. London and New York: Routledge and Kegan Paul, 1987. Pp. x + 197. $29.95 (cloth). Readers of Donagan expecting a book in the style of The Theory of Morality will be surprised; Choice: The Essential Element in Human Action is far more compact and demanding. In setting out to support his thesis that the "propositional attitudes" (the term is taken from Russell) of beliefs and wishes explain choices which, in turn, explain human actions, the author considers a plethora of views and objections of both contemporary and traditional philosophers: Gilbert Ryle-whose Concept of Mind Donagan considers a classic of analytic Aristotelianism -Roderick Chisholm, Donald Davidson, Anthony Kenny, John Searle, Alvin Goldman, Elizabeth Anscombe, Bertrand Russell, Plato, Aristotle, Aquinas, Wittgenstein, Quine, and Frege. At times the reader may wish that fewer theorists were appealed to, or perhaps that his or her familiarity with the views referred to were more extensive, or at least that (although not in the case of Frege) they were explicated in more detail. Further explication, however, could obscure hopelessly the line of reasoning of the author. While he appears to wish to give credit every place it is due, he also wishes to clarify the genesis of significant objections to be met by a defensible action theory. Happily, Donagan himself provides an overview of his project, which he calls a " Plan for an Investigation of Human Action on Socratic Lines." This is proffered in chapter one after the author has discussed the " Socratic tradition in the theory of human action " and the question "Should the Socratic tmdition be jettisoned as folk psychology?" BOOK REVIEWS 161 As these sections provide the foundation for Donagan's thesis, they are briefly summarized here. Considering both Aristotle and the " mediaeval Aristotelian " Aquinas to be in the Socratic tradition, Donagan emphasizes Aristotle's role in distinguishing human from animal action. Possibilities for acting are represented in the human intellect in propositions, toward which one can take various attitudes. Those philosophers who hold that such propositional attitudes cannot explain human action are challenged. Donagan then takes on those cognitive scientists who reject as " stagnant " and rooted in folk beliefs the Socratic theory of action. He rather impressively presents the problems involved in admitting, as do the " scientific psychologists," the practicality of employing the notion of propositional attitudes in history and natural sciences (which seem to exist in a context of history), while at the same time actually :rejecting the existence of such attitudes and hence their theoretical validity. Indeed, Donagan brings home the point that it is simply incon· sistent to hold both that there are no beliefs and that the belief that there are beliefs underlies a stagnant research program. Having thus sustained his position :regarding propositional attitudes in general, Donagan summarizes, chapter by chapter, his "contem· po:rary Socratic " plan for examining the actions of rational animals. It will be helpful to sketch this program, filling in crucial portions. In chapter two the author contends that bodily or mental actions are events that are individuals insofar as they are " changes or persistences in states of continuing individual objects" (p. 38). Propositional attitudes are states, but their arising and persistence in being as energeiai are events that explain,actions. Building on Aristotle's teaching and that of his mediaeval successors, in chapter three Donagan argues that beliefs and wishes, or the cognitive and appetitive propositional at· titudes, explain choices which in turn explain actions. In chapter four Donagan elucidates Durnmett's :revision of the Fregeau semantical theory, which he opts... (shrink)

Braitenberg et al.'s target article presents the best current integration of anatomical and physiological data, and provides a qualitative description of cerebellar function in terms of the dynamics of processes based on the geometry of the cerebellar cortex. We compare the proposed model to our own quantitative model based on the concept of Purkinjeunit.

The cholinergic system is a good candidate for the role of determining the relative weight given in cortical information processing to new sensory information versus prior knowledge. We discuss the physiological data supporting this, and suggest that this Bayesian perspective can easily be reconciled with the dynamical framework proposed by Behrendt & Young.

The study's purpose was to estimate the variety of foods consumed within standard and ethnic food categories by three groups of women between 18 and 35 years of age. Foreign-born Chinese women [N = 21], Chinese-American women [N = 20] and white American women [N = 23] kept 4-day food records, after instruction. Analysis of variance showed that the mean number of different foods consumed by the foreign-born Chinese was significantly [p < 0.05] lower than those eaten by the other (...) two groups for breads/cereals, dairy products, ethnic foods, fats, meats, sweets/sugars, and vegetable categories. White American women consumed significantly more dairy products and legumes/nuts than either of the groups of Chinese women. Diets of the Chinese-American women were more nutrient dense than those of the women in the other groups, containing significantly more energy, riboflavin, iron, folacin, and calcium than those of the foreign-born Chinese women. The percentage of kilocalories derived from fat [33–34%] did not differ among groups. 95% of foreign-born and 85% of Chinese-American women affirmed their ethnic identification by consuming foods belonging to Chinese cuisine; whereas, the percentage [30%] of white American women selecting Chinese food was significantly lower. Mexican and Italian foods were selected by significantly more white and Chinese-American women than by foreign-born Chinese women. Approximately 20% of both groups of Chinese women, but 49% of white American subjects, ate Japanese food. Chinese-American women retained a preference for Chinese food, similar to that of the foreign-born Chinese women. However, the Chinese-American women consumed cheeses, legumes, raw vegetables in salads, and foods from Italian and Mexican cuisines, indicating their acceptance of foods commonly consumed by white American women. Dietary acculturation among the Chinese-American women improved their diets over those of the foreign-born Chinese women and these results support the theory that consumption of a greater variety of foods increases nutrient density of diets. (shrink)

I have been supposing that for the theory of reasoning, explicit belief is an all-or-nothing matter, I have assumed that, as far as principles of reasoning are concerned, one either believes something explicitly or one does not; in other words an appropriate "representation" is either in one's "memory" or not. The principles of reasoning are principles for modifying such all-or-nothing representations. This is not to deny that in some ways belief is a matter of degree. For one thing implicit belief (...) is certainly a matter of degree, since it is a matter of how easily and automatically one can infer something from what one believes explicitly. Furthermore, explicit belief is a matter of degree in the sense that one believes some things more strongly than others. Sometimes one is only somewhat inclined to believe something, sometimes one is not sure what to believe, sometimes one is inclined to disbelieve something, sometimes one is quite confident something is not so, and so forth. (shrink)

Theories of adverbial modification can be roughly distinguished into two sorts. One kind of theory takes logical form to follow surface grammatical form. Adverbs are treated as unanalyzable logical operators that turn a predicate or sentence into a different predicate or sentence respectively. And new rules of logic are stated for these operators. -/- A different kind of theory does not suppose that logical form must parallel surface grammatical form. It allows that logical form may have more to do with (...) deeper structures that might be studied in transformational grammar. Adverbs are treated as surface forms of the underlying predicates represented by corresponding adjectives and verbs. 'Slowly' is derived from 'slow'; 'intentionally' from 'intentional' or 'intend'; etc. And new rules of logic are avoided where they can be. -/- In this paper I attempt to state some of the advantages of the second sort of theory. My procedure will be this. First, I will try to say in outline what theories of logical form are. Then I will state five principles for evaluating such theories. Next, I will sketch the sorts of analyses acceptance of principles (1)-(5) leads to. In particular I will talk about adverbial phrases (e.g. locatives) that are best analyzed in terms of implicit references to events, relative modifiers (like 'large') which relate something to a comparison class, and 'that' clauses taken as names of propositions. By appealing to principles (1)-(5) I will defend these analyses against certain others, one that appeals to many logical operators, a second that treats all sentences as names of propositions, and a third that sees implicit reference to possible worlds in the language being analyzed. Finally, I will offer a pragmatic defense of my approach in terms of principles (1)-(5) as against a different approach that appeals to possible world semantics. (shrink)

BonJour offers two main reasons for supposing that there is such a thing as rational insight into necessity. First, he says there are many examples in which it clearly seems that one has such insight. Second, he argues that any epistemology denying the existence of rational insight into necessity is committed to a narrow skepticism. After commenting about possible frameworks for epistemological justification, I argue against these two claims in reverse order.

This article offers a critique of Thomas Scanlon's well-known account of promissory obligation by reference to the rights of promisees. Scanlon's account invokes a moral principle, the "principle of fidelity". Now, corresponding to a promisor's obligation to perform is a promisee's right to performance. It is argued that one cannot account for this right in terms of Scanlon's principle. This is so in spite of a clause in the principle relating to the promisee's "consent", which might have been thought to (...) do the trick. Most likely this argument can be applied to all "moral principle" accounts of promissory obligation. An alternative both to these and to "social practice" accounts is needed. (shrink)

In Contested Reproduction, John Evans outlines the results of a major piece of sociological research he has conducted. Evans suspects that reproductive genetic technologies will be a significant issue in coming cultural conflicts in the United States and that religious perspectives will play an important role in determining the shape these conflicts take. If one believes that we are hopelessly and bitterly divided on such issues, then the shape of our future conflicts may simply pit one entrenched side against another. (...) Evans’ findings suggest that ordinary religious believers in the United States have rather complex views about these technologies—more shades of gray than black or white. He concludes that the coming conflicts may be neither as insuperable nor as hopeless as we sometimes suppose. Serious exchange, and not just caricature or dismissal, may characterize even our deep disagreements. Perhaps so. But a reading of Progress in Bioethics, a collection of essays edited by Jonathan D. Moreno and Sam Berger, might give one pause here, and not because of anything it reveals about the views of religious believers. (shrink)

Any acceptable account of moral epistemology must accord with the following points. (1) Different people acquire seemingly very different moralities. (2) All normal people acquire a moral sense, whether or not they are given explicit moral instruction. Language resembles morality in these ways. There is considerable evidence from linguistics for linguistic universals. This suggests that (3) despite the first point, there are moral universals. If so, it might be possible to develop a moral epistemology that is analogous to the theory (...) of universal grammar in linguistics. In what follows, I will try to sketch what might be involved in such a moral epistemology. (shrink)

The authors explore the simulating, philosophical question, "What is the importance of parks and recreation to the quality of life?". Asked by students, educators and practitioners alike, the answer to the question is the core of one's philosophy in the field of recreation. The text has been written so that it is easy to comprehend. The authors present the material in a first person plural and without gender biased language. Each section contains probing questions and a list of references.

Quine takes philosophy to be continuous with science. Proper philosophical method is scientific method applied self-consciously to problems more general than those ordinarily considered within a particular science. Science is self-conscious common sense; and philosophy is self-conscious science. In order to understand and answer a basic philosophical question such as "What exists?" we must know something of the results of particular sciences like physics, chemistry, mathematics, biology, astronomy, and psychology. To learn what we can from these sciences is to do (...) philosophy of science; and for our purposes, "philosophy of science is philosophy enough.". (shrink)

Health equity is a global concern. Although health equity extends far beyond the equitable distribution of healthcare, equitable access to healthcare is essential to the achievement of health equity. In Canada, Indigenous Peoples experience inequities in health and healthcare access. Cultural safety and trauma‐ and violence‐informed care have been proposed as models of care to improve healthcare access, yet practitioners lack guidance on how to implement these models. In this paper, we build upon an existing framework of equity‐oriented care for (...) primary healthcare settings by proposing strategies to guide nurses in operationalizing cultural safety and trauma‐ and violence‐informed care into nursing practice at the individual level. This component is one strategy to redress inequitable access to care among Indigenous Peoples in Canada. We conceptualize barriers to accessing healthcare as intrapersonal, interpersonal, and structural. We then define three domains for nursing action: practicing reflexivity, prioritizing relationships, and considering the context. We have applied this expanded framework within the context of Indigenous Peoples in Canada as a way of illustrating specific concepts and focusing our argument; however, this framework is relevant to other groups experiencing marginalizing conditions and inequitable access to healthcare, and thus is applicable to many areas of nursing practice. (shrink)

Pretendo mostrar que a indução enumerativa não deve, por si só, ser considerada uma forma garantida de inferência não-dedutiva. Eu afirmo que, nos casos em que uma inferência garantida aparentemente é um caso da indução enumerativa, a inferência deve ser descrita como um caso especial de outra forma de inferência, a qual eu denominarei “inferência da melhor explicação”.

Examining the author’s own experiences of narcotics addiction reveals certain aspects of the addicted mentality that have strong ethical valence. In general, this shows that addiction is not a state fundamentally characterized by lack. The rudiments of this position are found in some contemporary philosophy of addiction; also, it is contrasted with a common widely held mistaken view. Addiction should instead be understood in continuity with and as illuminating the nature of human personhood and subjectivity. Under a phenomenology specific to (...) the author’s experience, addiction appears as a mode of experience that has an unmanageable overflow of narratives created as discourses concerning people, events, thoughts, and feelings. (shrink)

Intentions are distinct real psychological states, not mere constructs out of beliefs and desires. One intends to do something only if one believes one will do it. Positive intentions are to be distinguished from negative and conditional intentions. All intentions are self‐referential and are to be distinguished from beliefs by means of differences between theoretical reasoning, which directly modifies beliefs, and practical reasoning, which directly modifies intentions. One can sometimes adopt intrinsic desires at will and one may pursue a plan (...) in order to give significance to earlier acts. (shrink)

How is one to act so as to do as well as possible according to one’s ranking of the possible outcomes? How—as it may be put—is one to act rationally? Sometimes the possible outcomes are not under one’s own control: an outcome is a combination of one’s own and another agent’s action. Often, then, one must try to work out what the other agent will do, in order to do as well as possible in one’s own lights. It is situations (...) of this sort—situations of “strategic interaction”—that most concern the game theorist. (shrink)

As nursing professionals, we believe access to healthcare is fundamental to health and that it is a determinant of health. Therefore, evidence suggesting access to healthcare is problematic for many Indigenous peoples is concerning. While biomedical perspectives underlie our current understanding of access, considering alternate perspectives could expand our awareness of and ability to address this issue. In this paper, we critique how access to healthcare is understood through a biomedical lens, how a postcolonial theoretical lens can extend that understanding, (...) and the subsequent implications this alternative view raises for the nursing profession. Drawing on peer‐reviewed published and gray literature concerning healthcare access and Indigenous peoples to inform this critique, we focus on the underlying theoretical lens shaping our current understanding of access. A postcolonial analysis provides a way of understanding healthcare as a social space and social relationship, presenting a unique perspective on access to healthcare. The novelty of this finding is of particular importance for the profession of nursing, as we are well situated to influence these social aspects, improving access to healthcare services broadly, and among Indigenous peoples specifically. (shrink)

Theories of causation may imply that your birth causes your death, which seems odd in the way that it is not odd to say that your birth precedes your death. Theories of knowledge may imply that the object of knowledge is the same as the object of belief, although we know but do not believe facts and we can know a proposition without knowing whether it is true.

Drawing on earlier work of the author that is both clarified and amplified here, this article explores the question: what is it for two or more people to intend to do something in the future? In short, what is it for people to share an intention? It argues for three criteria of adequacy for an account of shared intention (the disjunction, concurrence, and obligation criteria) and offers an account that satisfies them. According to this account, in technical terms explained in (...) the paper, people share an intention when and only when they are jointly committed to intend as a body to do such-and-such in the future. This account is compared and contrasted with the common approach that treats shared intention as a matter of the correlative personal intentions, with particular reference to the work of Michael Bratman. (shrink)

Comments on a defense of analyticity by Paul Boghossian that appeals to linguistic convention.

Scott Sehon argues for a complex view about the relation between commonsense psychology and the physical sciences.1 He rejects any sort of Cartesian dualism and believes that the common-sense psychological facts supervene on the physical facts. Nevertheless he asserts that there is an important respect in which common-sense psychology is independent of the physical sciences. Despite supervenience, we are not to expect any sort of reduction of common-sense psychology to physical science, nor are we to expect the physical sciences to (...) conflict with common-sense psychology. (shrink)

Psychological explanation is a kind of functional explanation, like some biological explanation, where the relevant functions tend to have to do with perceiving and acting in relation to the environment. Pain serves as a kind of alarm system; perception allows an organism to get information about the environment etc. Although there are defenders of a narrow, more solipsistic psychological functionalism, the dominant trend has involved the wider version. In any event, the wider functionalism is clearly more plausible and methodological solipsism (...) in psychology is incoherent. (shrink)